New Approaches to Blockade of the Renin-Angiotensin-Aldosterone System: Mineralocorticoid-Receptor Blockers Exert Antihypertensive and Renoprotective Effects Independently of the Renin-Angiotensin System

• Главные авторы: Akira Nishiyama (Автор), Koichi Hasegawa (Автор), Suwarni Diah (Автор), Hirofumi Hitomi (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2010-01-01T00:00:00Z.
• Предметы: article
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The role of angiotensin II in mediating hypertension and renal diseases is well documented, and inhibition of the renin-angiotensin-aldosterone system elicits antihypertensive and renoprotective effects. There is increasing evidence implicating aldosterone, in addition to angiotensin II, in the path...