Bioenergetic and Autophagic Characterization of Skin Fibroblasts from <i>C9orf72</i> Patients

• Main Authors: Maria Isabel Alvarez-Mora (Author), Gloria Garrabou (Author), Tamara Barcos (Author), Francisco Garcia-Garcia (Author), Ruben Grillo-Risco (Author), Emma Peruga (Author), Laura Gort (Author), Sergi Borrego-Écija (Author), Raquel Sanchez-Valle (Author), Judith Canto-Santos (Author), Paula Navarro-Navarro (Author), Laia Rodriguez-Revenga (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objective of this study is to describe the alterations occurring during the neurodegenerative process in skin fibroblast cultures from <i>C9orf72</i> patients. We characterized the oxidative stress, autophagy flux, small ubiquitin-related protein SUMO2/3 levels as well as the mitocho...