Epigenetic regulation of cancer progression by EZH2: from biological insights to therapeutic potential
Abstract Enhancer of zeste homolog 2 (EZH2), a histone methyltransferase and a catalytic component of PRC2, catalyzes tri-methylation of histone H3 at Lys 27 (H3K27me3) to regulate gene expression through epigenetic machinery. EZH2 also functions both as a transcriptional suppressor and a transcript...
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2018-03-01T00:00:00Z.
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