Photodynamic Therapy Targeting Macrophages Using IRDye700DX-Liposomes Decreases Experimental Arthritis Development

• Main Authors: Daphne N. Dorst (Author), Marti Boss (Author), Mark Rijpkema (Author), Birgitte Walgreen (Author), Monique M. A. Helsen (Author), Desirée L. Bos (Author), Louis van Bloois (Author), Gerrit Storm (Author), Maarten Brom (Author), Peter Laverman (Author), Peter M. van der Kraan (Author), Mijke Buitinga (Author), Marije I. Koenders (Author), Martin Gotthardt (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophages play a crucial role in the initiation and progression of rheumatoid arthritis (RA). Liposomes can be used to deliver therapeutics to macrophages by exploiting their phagocytic ability. However, since macrophages serve as the immune system's first responders, it is inadvisable to sys...