Quercetin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and activation of JAK2/STAT3 pathway: A target based networking pharmacology approach

• Main Authors: Di Wang (Author), Farman Ali (Author), Huixin Liu (Author), Ying Cheng (Author), Meizhu Wu (Author), Muhammad Zubair Saleem (Author), Huifang Zheng (Author), Lihui Wei (Author), Jiangfeng Chu (Author), Qiurong Xie (Author), Aling Shen (Author), Jun Peng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The rapid growth of vascular smooth muscle cells (VSMCs) represents crucial pathological changes during the development of hypertensive vascular remodeling. Although quercetin exhibits significantly therapeutic effects on antihypertension, the systematic role of quercetin and its exact mode of actio...