Polyamine pathway is associated with muscle anabolic effects by androgen receptor ligand

• Main Authors: Masanobu Kanou (Author), Katsuyuki Nakamura (Author), Kyohei Horie (Author), Hiroshi Sakai (Author), Yuta Yanagihara (Author), Iori Sakakibara (Author), Kei Yamana (Author), Yuuki Imai (Author)
• Format: Book
• Published: Wiley, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Muscle wasting is a common condition concomitant with aging. Androgens significantly increase skeletal muscle mass, but the role of the androgen receptor (AR) in skeletal muscle is not well established. TEI‐SARM2, a novel selective androgen receptor modulator (SARM), was develope...