Herbal compound 861 prevents hepatic fibrosis by inhibiting the TGF-β1/Smad/SnoN pathway in bile duct-ligated rats

• Main Authors: Cheng Chi (Author), Xiao-ya Liu (Author), Fei Hou (Author), Xiao-zheng Yu (Author), Chun-yun Li (Author), Li-jian Cui (Author), Rui-xia Liu (Author), Cheng-hong Yin (Author)
• Format: Book
• Published: BMC, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background This study was to evaluate the effects of herbal compound 861 (Cpd861) on ski-related novel protein N (SnoN) and transforming growth factor-β1 (TGF-β1) /Smad signaling in rats with bile duct ligation (BDL)-induced hepatic fibrosis, and to explore the mechanisms of Cpd861 on hepat...