A Sustained Reduction in Serum Cholinesterase Enzyme Activity Predicts Patient Outcome following Sepsis

• Main Authors: Aleksandar R. Zivkovic (Author), Sebastian O. Decker (Author), Anne C. Zirnstein (Author), Annette Sigl (Author), Karsten Schmidt (Author), Markus A. Weigand (Author), Stefan Hofer (Author), Thorsten Brenner (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Early sepsis identification is of paramount importance for an effective therapy and the patient outcome; however, a suitable prognostic biomarker is lacking. Anti-inflammatory nonneuronal cholinergic signaling modulates the magnitude of an immune response. Serum cholinesterase (BChE), an enzyme that...