Semisynthetic Amides of Amphotericin B and Nystatin A<sub>1</sub>: A Comparative Study of In Vitro Activity/Toxicity Ratio in Relation to Selectivity to Ergosterol Membranes
Polyene antifungal amphotericin B (AmB) has been used for over 60 years, and remains a valuable clinical treatment for systemic mycoses, due to its broad antifungal activity and low rate of emerging resistance. There is no consensus on how exactly it kills fungal cells but it is certain that AmB and...
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Format: | Book |
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MDPI AG,
2023-01-01T00:00:00Z.
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A1234.567 |
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