The emergence of cell-based protein arrays to test for polyspecific off-target binding of antibody therapeutics
Specificity profiling is a requirement for monoclonal antibodies (mAbs) and antibody-directed biotherapeutics such as CAR-T cells prior to initiating human trials. However, traditional approaches to assess the specificity of mAbs, primarily tissue cross-reactivity studies, have been unreliable, lead...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2024-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
| Call Number: |
A1234.567 |
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| Copy 1 | Available |