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Application of Physiologically Based Pharmacokinetic Modeling to Predict Maternal Pharmacokinetics and Fetal Exposure to Oxcarbazepine

Pregnancy is associated with physiological changes that may affect drug pharmacokinetics (PKs). The aim of this study was to establish a maternal-fetal physiologically based pharmacokinetic (PBPK) model of oxcarbazepine (OXC) and its active metabolite, 10,11-dihydro-10-hydroxy-carbazepine (MHD), to...

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Bibliographic Details
Main Authors:	Lixia He (Author), Meng Ke (Author), Wanhong Wu (Author), Jiarui Chen (Author), Guimu Guo (Author), Rongfang Lin (Author), Pinfang Huang (Author), Cuihong Lin (Author)
Format:	Book
Published:	MDPI AG, 2022-11-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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