Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway

• Main Authors: Tianyuan Liu (Author), Huimin Gao (Author), Yueyi Zhang (Author), Shan Wang (Author), Meixi Lu (Author), Xuan Dai (Author), Yage Liu (Author), Hanfen Shi (Author), Tianshu Xu (Author), Jiyuan Yin (Author), Sihua Gao (Author), Lili Wang (Author), Dongwei Zhang (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hyperuricemia (HUA) is a kind of metabolic disease with high incidence that still needs new countermeasures. Apigenin has uric-lowering and kidney-protective activities, but how apigenin attenuates HUA and renal injury remains largely unexploited. To this end, an acute HUA mouse model was establishe...