Potent inhibition of Junín virus infection by interferon in murine cells.

• Main Authors: Cheng Huang (Author), Aida G Walker (Author), Ashley M Grant (Author), Olga A Kolokoltsova (Author), Nadezhda E Yun (Author), Alexey V Seregin (Author), Slobodan Paessler (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The new world arenavirus Junín virus (JUNV) is the causative agent of Argentine hemorrhagic fever, a lethal human infectious disease. Adult laboratory mice are generally resistant to peripheral infection by JUNV. The mechanism underlying the mouse resistance to JUNV infection is largely unknown. We...