A rare association between factor H deficiency and lupus: Case report and experimental treatment with curcumin

• Main Authors: Ana Catarina Lunz Macedo (Author), Lazara Elena Santisteban Lores (Author), José Antonio Tavares Albuquerque (Author), Nilo José Coelho Duarte (Author), Paschoalina Romano (Author), Persio Almeida Rezende Ebner (Author), Vinicius Marcondes Rezende (Author), Clovis A. Silva (Author), Luís Eduardo Coelho Andrade (Author), Dewton Moraes Vasconcelos (Author), Lourdes Isaac (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Factor H (FH) is one of the most important regulatory proteins of the alternative pathway of the complement system. FH deficiency is a rare condition that causes unregulated C3 consumption, leading to an increased susceptibility to infections and glomerulopathies. Our previous studies have demonstra...