Therapeutic Drug Monitoring of Mycophenolic Acid as a Precision Medicine Tool for Heart Transplant Patients: Results of an Observational Pharmacokinetic Pilot Study

• Main Authors: Francesco Lo Re (Author), Jacopo Angelini (Author), Sandro Sponga (Author), Chiara Nalli (Author), Antonella Zucchetto (Author), Jessica Biasizzo (Author), Ugolino Livi (Author), Massimo Baraldo (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the clinical practice management of heart transplant (HTx), the impact of calcineurin inhibitors co-administration on pharmacokinetics (PKs) of mycophenolic acid (MPA), mycophenolate mofetil (MMF) active drug, is not adequately considered. This retrospective study investigated full MPA-PK profile...