Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1

• Main Authors: Michael J. Peluso (Author), Cassandra Thanh (Author), Cecilia A. Prator (Author), Louise E. Hogan (Author), Victor M. Arechiga (Author), Sophie Stephenson (Author), Philip J. Norris (Author), Clara Di Germanio (Author), Dietmar Fuchs (Author), Henrik Zetterberg (Author), Steven G. Deeks (Author), Magnus Gisslén (Author), Richard W. Price (Author), Timothy J. Henrich (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: The aim of this study was to assess soluble CD30 (sCD30), a protein that colocalises with HIV-1 RNA and DNA in lymphoid cells and tissues, in cerebrospinal fluid (CSF) as a marker of HIV-1 infection in the central nervous system (CNS). Methods: This was a cross-sectional study using arch...