Altered Left Ventricular Ion Channel Transcriptome in a High-Fat-Fed Rat Model of Obesity: Insight into Obesity-Induced Arrhythmogenesis

• Main Authors: Reza Ashrafi (Author), Marianne Yon (Author), Lucy Pickavance (Author), Joseph Yanni Gerges (Author), Gershan Davis (Author), John Wilding (Author), Kun Jian (Author), Henggui Zhang (Author), George Hart (Author), Mark Boyett (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction. Obesity is increasingly common and is associated with an increased prevalence of cardiac arrhythmias. The aim of this study was to see whether in obesity there is proarrhythmic gene expression of ventricular ion channels and related molecules. Methods and Results. Rats were fed on a hi...