CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity.

• Main Authors: Kristin Moderzynski (Author), Stefanie Papp (Author), Jessica Rauch (Author), Liza Heine (Author), Svenja Kuehl (Author), Ulricke Richardt (Author), Bernhard Fleischer (Author), Anke Osterloh (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rickettsia typhi is an intracellular bacterium that causes endemic typhus, a febrile disease that can be fatal due to complications including pneumonia, hepatitis and meningoencephalitis, the latter being a regular outcome in T and B cell-deficient C57BL/6 RAG1-/- mice upon Rickettsia typhi infectio...