Dimethyl Fumarate Mediates Sustained Vascular Smooth Muscle Cell Remodeling in a Mouse Model of Cerebral Aneurysm

• Main Authors: Alejandra N. Martinez (Author), Giovane G. Tortelote (Author), Crissey L. Pascale (Author), Uduak-Obong I. Ekanem (Author), Ana Paula de O. Leite (Author), Isabella G. McCormack (Author), Aaron S. Dumont (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cerebral aneurysms (CA) are a type of vascular disease that causes significant morbidity and mortality with rupture. Dysfunction of the vascular smooth muscle cells (VSMCs) from circle of Willis (CoW) vessels mediates CA formation, as they are the major cell type of the arterial wall and play a role...