CYP1A1 methylation mediates the effect of smoking and occupational polycyclic aromatic hydrocarbons co-exposure on oxidative DNA damage among Chinese coke-oven workers

• Main Authors: Yanli Liu (Author), Xuejing Li (Author), Bin Zhang (Author), Ye Fu (Author), Aimin Yang (Author), Hongjie Zhang (Author), Huitao Zhang (Author), Yingying Niu (Author), Jisheng Nie (Author), Jin Yang (Author)
• Format: Book
• Published: BMC, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Multiple factors, including co-exposure between lifestyle and environmental risks, are important in susceptibility to oxidative DNA damage. However, the underlying mechanism is not fully understood. This study was undertaken to evaluate whether Cytochrome P4501A1 (CYP1A1) methyla...