7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors

A series of 3H-1,2-benzoxathiepine 2,2-dioxides incorporating 7-acylamino moieties were obtained by an original procedure starting from 5-nitrosalicylaldehyde, which was treated with propenylsulfonyl chloride followed by Wittig reaction of the bis-olefin intermediate. The new derivatives, belonging...

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Main Authors: Aleksandrs Pustenko (Author), Alessio Nocentini (Author), Anastasija Balašova (Author), Mikhail Krasavin (Author), Raivis Žalubovskis (Author), Claudiu T. Supuran (Author)
Formato: Livro
Publicado em: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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