Effects of pH on Nifekalant-Induced Electrophysiological Change Assessed in the Langendorff Heart Model of Guinea Pigs

Since information regarding the effects of pH on the extent of nifekalant-induced repolarization delay and torsades de pointes remains limited, we assessed it with a Langendorff heart model of guinea pigs. First, we investigated the effects of pH change from 7.4 to 6.4 on the bipolar electrogram sim...

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Main Authors: Katsuyuki Kazusa (Author), Yuji Nakamura (Author), Yudai Watanabe (Author), Kentaro Ando (Author), Atsushi Sugiyama (Author)
Format: Book
Published: Elsevier, 2014-01-01T00:00:00Z.
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