Stable Transcriptional Repression and Parasitism of HIV-1

• Main Authors: Surya Shrivastava (Author), Paige Charlins (Author), Amanda Ackley (Author), Heather Embree (Author), Boro Dropulic (Author), Ramesh Akkina (Author), Marc S. Weinberg (Author), Kevin V. Morris (Author)
• Format: Book
• Published: Elsevier, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gene-based therapies represent a promising treatment for HIV-1 infection, as they offer the potential for sustained viral inhibition and reduced treatment interventions. One approach developed here involves using conditionally replicating vectors (CR-vectors). CR-vectors utilize HIV-expressed protei...