Relevance of Liquid-Liquid Phase Separation of Supersaturated Solution in Oral Absorption of Albendazole from Amorphous Solid Dispersions

• Main Authors: Kyosuke Suzuki (Author), Kohsaku Kawakami (Author), Masafumi Fukiage (Author), Michinori Oikawa (Author), Yohei Nishida (Author), Maki Matsuda (Author), Takuya Fujita (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amorphous solid dispersion (ASD) is one of the most promising formulation technologies for improving the oral absorption of poorly soluble drugs, where the maintenance of supersaturation plays a key role in enhancing the absorption process. However, quantitative prediction of oral absorption from AS...