Evolution from small molecule to nano-drug delivery systems: An emerging approach for cancer therapy of ursolic acid

• Main Authors: Jingwei Shao (Author), Yifan Fang (Author), Ruirui Zhao (Author), Fangmin Chen (Author), Mingyue Yang (Author), Jiali Jiang (Author), Zixuan Chen (Author), Xiaotian Yuan (Author), Lee Jia (Author)
• Format: Book
• Published: Elsevier, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ursolic acid (UA), a natural pentacyclic triterpenoid, possesses widespread biological and pharmacological activities. However, drawbacks such as low bioavailability, poor targeting and rapid metabolism greatly hinder its further clinical application. Recently, with the development of nanotechnology...