A model-based optimization strategy to achieve fast and robust freeze-drying cycles
Freeze-drying is a time and cost-intensive process. The primary drying phase is the main target in a process optimization exercise. Biopharmaceuticals require an amorphous matrix for stabilization, which may collapse during primary drying if the critical temperature of the formulation is exceeded. T...
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| Autori principali: | , , , , , |
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| Natura: | Libro |
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Elsevier,
2023-12-01T00:00:00Z.
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