A comprehensive lipidomic screen of pancreatic β-cells using mass spectroscopy defines novel features of glucose-stimulated turnover of neutral lipids, sphingolipids and plasmalogens

• Ngā kaituhi matua: Gemma L. Pearson (Author), Natalie Mellett (Author), Kwan Yi Chu (Author), Ebru Boslem (Author), Peter J. Meikle (Author), Trevor J. Biden (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2016-06-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Objective: Glucose promotes lipid remodelling in pancreatic β-cells, and this is thought to contribute to the regulation of insulin secretion, but the metabolic pathways and potential signalling intermediates have not been fully elaborated. Methods: Using mass spectrometry (MS) we quantified changes...