Physiologically‐Based Pharmacokinetic Modeling for the Prediction of CYP2D6‐Mediated Gene-Drug-Drug Interactions
The aim of this work was to predict the extent of Cytochrome P450 2D6 (CYP2D6)‐mediated drug-drug interactions (DDIs) in different CYP2D6 genotypes using physiologically‐based pharmacokinetic (PBPK) modeling. Following the development of a new duloxetine model and optimization of a paroxetine model,...
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| Main Authors: | , , |
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| Format: | Book |
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Wiley,
2019-08-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
| Call Number: |
A1234.567 |
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| Copy 1 | Available |