lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1

• Main Authors: Duan Li (Author), Xiaoyan Wang (Author), Yujie Dang (Author), Xinyue Zhang (Author), Shidou Zhao (Author), Gang Lu (Author), Wai-Yee Chan (Author), Peter C.K. Leung (Author), Yingying Qin (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dysfunction of granulosa cells (GCs) leading to follicle atresia has been extensively studied as a major cause of premature ovarian insufficiency (POI), but the regulatory role of long non-coding RNAs (lncRNAs) in this process is still poorly understood. Here, we show that the lncRNA LINC02690 or GC...