Eptinezumab administered intravenously, subcutaneously, or intramuscularly in healthy subjects and/or patients with migraine: Early development studies

• Main Authors: Brian Baker (Author), Vivienne Shen (Author), Roger Cady (Author), Anders Ettrup (Author), Frank Larsen (Author)
• Format: Book
• Published: SAGE Publishing, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To report the safety, tolerability, and pharmacokinetics/pharmacodynamics (PK/PD) of eptinezumab using intravenous (IV) infusion compared to other routes of administration from two phase 1 trials. Methods: Study 1 (NCT01579383) and Study 2 (ACTRN12615000531516) were double-blind, placebo-...