Neutrophils Isolated from Septic Patients Exhibit Elevated Uptake of Vitamin C and Normal Intracellular Concentrations despite a Low Vitamin C Milieu

Neutrophils Isolated from Septic Patients Exhibit Elevated Uptake of Vitamin C and Normal Intracellular Concentrations despite a Low Vitamin C Milieu

Vitamin C (ascorbate) plays an important role in neutrophil function and is accumulated by the cells either directly via vitamin C transporters (SVCT) or indirectly following oxidation to dehydroascorbic acid. Septic patients are known to have significantly depleted plasma ascorbate status, but litt...

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Main Authors: Anitra C. Carr (Author), Stephanie Bozonet (Author), Juliet Pullar (Author), Emma Spencer (Author), Patrice Rosengrave (Author), Geoff Shaw (Author)
Format: Book
Published: MDPI AG, 2021-10-01T00:00:00Z.
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3rd Floor Main Library

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