Exploiting next-generation sequencing in antibody selections - a simple PCR method to recover binders

• 主要な著者: Fortunato Ferrara (著者), Andre A. Teixeira (著者), Leslie Naranjo (著者), M. Frank Erasmus (著者), Sara D'Angelo (著者), Andrew R.M. Bradbury (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Antibody discovery using invitro display technologies such as phage and/or yeast display has become acornerstone in many research and development projects, including the creation of new drugs for clinical use. Traditionally, after the selection phase, random clones are isolated for binding validatio...