Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway

• Автори: Jianyou Gu (Автор), Yu Zhang (Автор), Xiao Wang (Автор), Jingjing Xiang (Автор), Shu Deng (Автор), Dijiong Wu (Автор), Junfa Chen (Автор), Lihong Yu (Автор), Yan Zhou (Автор), Yaokun Wang (Автор), Jianping Shen (Автор)
• Формат: Книга
• Опубліковано: BMC, 2020-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background C-Myc overexpression is associated with poor prognosis and aggressive progression of natural killer/T-cell lymphoma (NKTCL). Matrine, a main alkaloid of the traditional Chinese herb Sophora flavescens Ait, has been shown to inhibit cellular proliferation and induce apoptosis of v...