Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway

• Main Authors: Jianyou Gu (Author), Yu Zhang (Author), Xiao Wang (Author), Jingjing Xiang (Author), Shu Deng (Author), Dijiong Wu (Author), Junfa Chen (Author), Lihong Yu (Author), Yan Zhou (Author), Yaokun Wang (Author), Jianping Shen (Author)
• Format: Book
• Published: BMC, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background C-Myc overexpression is associated with poor prognosis and aggressive progression of natural killer/T-cell lymphoma (NKTCL). Matrine, a main alkaloid of the traditional Chinese herb Sophora flavescens Ait, has been shown to inhibit cellular proliferation and induce apoptosis of v...