Pulmonary immunization: deposition site is of minor relevance for influenza vaccination but deep lung deposition is crucial for hepatitis B vaccination

• Main Authors: Jasmine Tomar (Author), Wouter F. Tonnis (Author), Harshad P. Patil (Author), Anne H. de boer (Author), Paul Hagedoorn (Author), Rita Vanbever (Author), Henderik W. Frijlink (Author), Wouter L.J. Hinrichs (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vaccination via the pulmonary route could be an attractive alternative to parenteral administration. Research towards the best site of antigen deposition within the lungs to induce optimal immune responses has conflicting results which might be dependent on the type of vaccine and/or its physical st...