De Novo Duplication of 11p15 Associated With Congenital Diaphragmatic Hernia

• Main Authors: Gabriel C. Dworschak (Author), Hartmut Engels (Author), Jessica Becker (Author), Lukas Soellner (Author), Thomas Eggermann (Author), Florian Kipfmueller (Author), Andreas Müller (Author), Heiko Reutter (Author), Martina Kreiß (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Congenital diaphragmatic hernia (CDH) is a rare defect of the diaphragm commonly associated with high morbidity and mortality due to lung hypoplasia and pulmonary hypertension. Although in 70% of patients the etiology of a CDH remains unknown, a multitude of causative chromosomal aberrat...