The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells

• المؤلفون الرئيسيون: Kristian Leisegang (مؤلف), Ralf Henkel (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2018-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Cytokines and hormones, including insulin, are known to modulate the hypothalamic-pituitary-testes axis and steroidogenesis, both centrally and peripherally. In the context of chronic inflammation and hyperinsulinaemia mediating male hypogonadism associated with obesity, metaboli...