Concanavalin-A Shows Synergistic Cytotoxicity with Tamoxifen via Inducing Apoptosis in Estrogen Receptor-Positive Breast Cancer: In Vitro and Molecular Docking Studies
Background: Tamoxifen (TAM) is the main treatment of estrogen receptor (ER)-positive breast cancer, however; its adverse effects and development of resistance hinder its use. Concanavalin A (Con A) is a mannose/glucose-binding lectin that has been reported to induce apoptosis in a variety of cell li...
Saved in:
Main Authors: | Mohamed Elshal (Author), Norhan Eid (Author), Ibrahim El-Sayed (Author), Wael El-Sayed (Author), Ahmed Ali Al-Karmalawy (Author) |
---|---|
Format: | Book |
Published: |
Tabriz University of Medical Sciences,
2022-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Tamoxifen non-estrogen receptor mediated molecular targets
by: Tatiana Bogush, et al.
Published: (2012) -
Click chemistry based synthesis, cytotoxic activity and molecular docking of novel triazole-thienopyrimidine hybrid glycosides targeting EGFR
by: Reham R. Khattab, et al.
Published: (2021) -
Cytotoxic effects of extracts obtained from plants of the Oleaceae family: bio-guided isolation and molecular docking of new secoiridoids from Jasminum humile
by: Khaled Ahmed Mansour, et al.
Published: (2022) -
Nα-1, 3-Benzenedicarbonyl-Bis-(Amino Acid) and Dipeptide Candidates: Synthesis, Cytotoxic, Antimicrobial and Molecular Docking Investigation
by: Naglah AM, et al.
Published: (2021) -
Synergistic Effects of Lauryl Gallate and Tamoxifen on Human Breast Cancer Cell
by: Keihan GHATREH SAMANI, et al.
Published: (2020)