ISO, via Upregulating MiR-137 Transcription, Inhibits GSK3β-HSP70-MMP-2 Axis, Resulting in Attenuating Urothelial Cancer Invasion
Our most recent studies demonstrate that miR-137 is downregulated in human bladder cancer (BC) tissues, while treatment of human BC cells with isorhapontigenin (ISO) elevates miR-137 abundance. Since ISO showed a strong inhibition of invasive BC formation in the N-butyl-N-(4-hydroxybutyl) nitrosamin...
Saved in:
Main Authors: | Xirui Guo (Author), Haishan Huang (Author), Honglei Jin (Author), Jiheng Xu (Author), Sanjiv Risal (Author), Jingxia Li (Author), Xin Li (Author), Huiying Yan (Author), Xingruo Zeng (Author), Lei Xue (Author), Changyan Chen (Author), Chuanshu Huang (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2018-09-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
ATG7 Overexpression Is Crucial for Tumorigenic Growth of Bladder Cancer In Vitro and In Vivo by Targeting the ETS2/miRNA196b/FOXO1/p27 Axis
by: Junlan Zhu, et al.
Published: (2017) -
lncRNA SNHG1 Promotes Basal Bladder Cancer Invasion via Interaction with PP2A Catalytic Subunit and Induction of Autophagy
by: Jiheng Xu, et al.
Published: (2020) -
The HSP90 Inhibitor, 17-AAG, Influences the Activation and Proliferation of T Lymphocytes via AKT/GSK3β Signaling in MRL/lpr Mice
by: Hong LJ, et al.
Published: (2020) -
Molecular Docking, Bioinformatic Analysis, and Experimental Verification for the Effect of Naringin on ADHD: Possible Inhibition of GSK-3β and HSP90
by: Hatem I. Mokhtar, et al.
Published: (2024) -
MEG3, as a Competing Endogenous RNA, Binds with miR-27a to Promote PHLPP2 Protein Translation and Impairs Bladder Cancer Invasion
by: Chao Huang, et al.
Published: (2019)