Role of Na+/Ca2+ Exchanger-Mediated Ca2+ Entry in Pressure-Induced Myogenic Constriction in Rat Posterior Cerebral Arteries

• Main Authors: Toshihide Kashihara (Author), Koichi Nakayama (Author), Toshio Matsuda (Author), Akemichi Baba (Author), Tomohisa Ishikawa (Author)
• 格式: 图书
• 出版: Elsevier, 2009-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract.: The involvement of Ca2+ entry via the Na+/Ca2+ exchanger (NCX) in myogenic constriction of rat posterior cerebral arteries was investigated. RT-PCR identified mRNA for NCX1, 2, and 3 in the arteries. Na+ removal increased [Ca2+]i, which was reduced by the NCX inhibitor SEA0400. SEA0400 in...