Mitochondrial inhibitor as a new class of insulin sensitizer

Insulin resistance is a major risk factor for type 2 diabetes. AMP-activated protein kinase (AMPK) is a drug target in the improvement of insulin sensitivity. Several insulin-sensitizing medicines are able to activate AMPK through inhibition of mitochondrial functions. These drugs, such as metformin...

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Hoofdauteurs: Yong Zhang (Auteur), Jianping Ye (Auteur)
Formaat: Boek
Gepubliceerd in: Elsevier, 2012-08-01T00:00:00Z.
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