Role of Presenilin in Mitochondrial Oxidative Stress and Neurodegeneration in Caenorhabditis elegans

• Váldodahkkit: Shaarika Sarasija (Dahkki), Kenneth R. Norman (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2018-08-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Neurodegenerative diseases like Alzheimer’s disease (AD) are poised to become a global health crisis, and therefore understanding the mechanisms underlying the pathogenesis is critical for the development of therapeutic strategies. Mutations in genes encoding presenilin (PSEN) occur in mos...