Concentrations of oocyte secreted GDF9 and BMP15 decrease with MII transition during human IVM

• Main Authors: Jesús Cadenas (Author), Susanne Elisabeth Pors (Author), Ajay Kumar (Author), Bhanu Kalra (Author), Stine Gry Kristensen (Author), Claus Yding Andersen (Author), Linn Salto Mamsen (Author)
• Format: Book
• Published: BMC, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The suggested effects of the oocyte secreted GDF9 and BMP15 growth factors on oocyte maturation are currently based on recombinant proteins, and little is known about native GDF9 and BMP15 in humans. Methods Human immature cumulus-oocyte complexes (COCs) obtained in connection wi...