Treatment With LAU-7b Complements CFTR Modulator Therapy by Improving Lung Physiology and Normalizing Lipid Imbalance Associated With CF Lung Disease

• Main Authors: Amanda Centorame (Author), Daciana Catalina Dumut (Author), Mina Youssef (Author), Martin Ondra (Author), Irenej Kianicka (Author), Juhi Shah (Author), Radu Alexandru Paun (Author), Tomas Ozdian (Author), John W. Hanrahan (Author), Ekaterina Gusev (Author), Basil Petrof (Author), Marian Hajduch (Author), Radu Pislariu (Author), Juan Bautista De Sanctis (Author), Danuta Radzioch (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic fibrosis (CF) is the most common autosomal recessive genetic disease in Caucasians, affecting more than 100,000 individuals worldwide. It is caused by pathogenic variants in the gene encoding CFTR, an anion channel at the plasma membrane of epithelial and other cells. Many CF pathogenic varia...