Identification and synthesis of metabolites of the new 4.5-dihydroisoxazol-5-carboxamide derivate Authors

• Main Authors: Alexander L. Khokhlov (Author), Ilya I. Yaichkov (Author), Mikhail A. Alexeev (Author), Mikhail K. Korsakov (Author), Anton A. Shetnev (Author), Sergey A. Ivanovsky (Author), Nikita N. Volkhin (Author), Sergey S. Petukhov (Author), Elena A. Vasilyeva (Author)
• Format: Book
• Published: Belgorod National Research University, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: 3-(2-butyl-5-chloro-1H-imidazole-4-yl)-N-[4-methoxy-3-(trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazole-5-carboxamide is new antirheumatic drug. It is necessary to identify and synthesize the biotransformation products for its complete pharmacokinetic study. Materials and Methods: A bio...