Metformin Facilitates Osteoblastic Differentiation and M2 Macrophage Polarization by PI3K/AKT/mTOR Pathway in Human Umbilical Cord Mesenchymal Stem Cells

• Principais autores: Min Shen (Autor), Huihui Yu (Autor), Yunfeng Jin (Autor), Jiahang Mo (Autor), Jingni Sui (Autor), Xiaohan Qian (Autor), Tong Chen (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2022-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Mesenchymal stem cells (MSCs) are the most promising multipotent stem cells that can differentiate into osteoblasts, chondrocytes, and adipocytes. This cellular flexibility contributes to widespread clinical use of MSCs in tissue repair and regeneration. The immune system is a key player in regulati...