A forebrain-hypothalamic ER stress driven circuit mediates hepatic steatosis during obesity

• Main Authors: Katherine Blackmore (Author), Claire J. Houchen (Author), Hayk Simonyan (Author), Hovhannes Arestakesyan (Author), Alyssa K. Stark (Author), Samantha A. Dow (Author), Han Rae Kim (Author), Jin Kwon Jeong (Author), Anastas Popratiloff (Author), Colin N. Young (Author)
• Format: Book
• Published: Elsevier, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Non-alcoholic fatty liver disease (NAFLD) affects 1 in 3 adults and contributes to advanced liver injury and cardiometabolic disease. While recent evidence points to involvement of the brain in NAFLD, the downstream neural circuits and neuronal molecular mechanisms involved in this respon...