Interleukin-6-elicited chronic neuroinflammation may decrease survival but is not sufficient to drive disease progression in a mouse model of Leigh syndrome

• Main Authors: Kevin Aguilar (Author), Carla Canal (Author), Gemma Comes (Author), Sandra Díaz-Clavero (Author), Maria Angeles Llanos (Author), Albert Quintana (Author), Elisenda Sanz (Author), Juan Hidalgo (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mitochondrial diseases (MDs) are genetic disorders characterized by dysfunctions in mitochondria. Clinical data suggest that additional factors, beyond genetics, contribute to the onset and progression of this group of diseases, but these influencing factors remain largely unknow...