Current Approaches to Monitor Macromolecules Directly from the Cerebral Interstitial Fluid

• Main Authors: Marie-Laure Custers (Author), Liam Nestor (Author), Dimitri De Bundel (Author), Ann Van Eeckhaut (Author), Ilse Smolders (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gaining insights into the pharmacokinetic and pharmacodynamic properties of lead compounds is crucial during drug development processes. When it comes to the treatment of brain diseases, collecting information at the site of action is challenging. There are only a few techniques available that allow...