TGF-β1 Inhibition of ACE2 Mediated by miRNA Uncovers Novel Mechanism of SARS-CoV-2 Pathogenesis

• Үндсэн зохиолчид: Ewelina D. Hejenkowska (Зохиогч), Nilay Mitash (Зохиогч), Joshua E. Donovan (Зохиогч), Anvita Chandra (Зохиогч), Carol Bertrand (Зохиогч), Chiara De Santi (Зохиогч), Catherine M. Greene (Зохиогч), Fangping Mu (Зохиогч), Agnieszka Swiatecka-Urban (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Karger Publishers, 2023-08-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for COVID-19, utilizes receptor binding domain (RBD) of spike glycoprotein to interact with angiotensin (Ang)-converting enzyme 2 (ACE2). Altering ACE2 levels may affect entry of SARS-CoV-2 and recovery from COVID-19. Decr...